2017

CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis
Sonneville, R., Moreno, S.P., Knebel, A., Johnson, C., Hastie, C.J., Gartner, A., Gambus, A. and Labib, K.
Nature cell biology, 2017, 19(5), pp.468-479

Molecular recognition in mitochondrial cytochromes P450 that catalyze the terminal steps of corticosteroid biosynthesis
Peng, H.M. and Auchus, R.J.
Biochemistry, 2017 56(17), pp.2282-2293

Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling
Yoon, J., Kim, S.B., Ahmed, G., Shay, J.W. and Terman, J.R.
Developmental Cell (2017)

Sortilin 1 Loss-of-Function Protects Against Cholestatic Liver Injury by Attenuating Hepatic Bile Acid Accumulation in Bile Duct Ligated Mice
Li, J., Woolbright, B.L., Zhao, W., Wang, Y., Matye, D., Hagenbuch, B., Jaeschke, H. and Li, T.
Toxicological Sciences 2017, p.kfx078

A Multidimensional Analytical Comparison of Remicade and the Biosimilar Remsima
Pisupati, K., Tian, Y., Okbazghi, S., Benet, A., Ackermann, R., Ford, M., Saveliev, S., Hosfield, C.M., Urh, M., Carlson, E. and Becker, C.
Analytical Chemistry, 2017, 89(9), pp.4838-4846.

Germinal‐center kinase‐like kinase co‐crystal structure reveals a swapped activation loop and C‐terminal extension
Marcotte, D., Rushe, M., M Arduini, R., Lukacs, C., Atkins, K., Sun, X., Little, K., Cullivan, M., Paramasivam, M., Patterson, T.A. and Hesson, T.
Protein Science, 2017, 26(2), pp.152-162.

GARLH Family Proteins Stabilize GABA A Receptors at Synapses
Yamasaki, T., Hoyos-Ramirez, E., Martenson, J.S., Morimoto-Tomita, M. and Tomita, S.
Neuron, 2017, 93(5), pp.1138-1152

Sortilin 1 modulates hepatic cholesterol lipotoxicity in mice via functional interaction with liver carboxylesterase 1
Li, J., Wang, Y., Matye, D.J., Chavan, H., Krishnamurthy, P., Li, F. and Li, T.
Journal of Biological Chemistry, 2017, 292(1), pp.146-160.

An inhibitory mono-ubiquitylation of the Drosophila initiator caspase Dronc functions in both apoptotic and non-apoptotic pathways
Kaya, H.E.K., Ditzel, M., Meier, P. and Bergmann, A.
PLoS genetics, 2017,13(2), p.e1006438.

Arylphorin is a mitogen in the Heliothis virescens midgut cell secretome upon Cry1Ac intoxication
Castagnola, A., Jackson, J., Perera, O.P., Oppert, C., Eda, S. and Jurat-Fuentes, J.L.
PeerJ Preprints 2017. (No. e2878v1).

Arginine methylation regulates c-Myc-dependent transcription by altering promoter recruitment of the acetyltransferase p300
Tikhanovich, I., Zhao, J., Bridges, B., Kumer, S., Roberts, B. and Weinman, S.A.
Journal of Biological Chemistry, 2017, pp.jbc-M117.

Cigarette Smoking‐Associated Alterations in Serotonin/Adrenalin Signaling Pathways of Platelets
Lowery, C.L., Elliott, C., Cooper, A., Hadden, C., Sonon, R.N., Azadi, P., Williams, D.K., Marsh, J.D., Woulfe, D.S. and Kilic, F.
Journal of the American Heart Association, 2017, 6(5), p.e005465.

Identification of Posttranslational Modifications of Endogenous Chromatin Proteins From Testicular Cells by Mass Spectrometry
Gupta, N., Pentakota, S., Mishra, L.N., Jones, R. and Rao, M.R.S.
Methods in Enzymology, 2017, 586, pp.115-142

Crystallization of a fungal lytic polysaccharide monooxygenase expressed from glycoengineered Pichia pastoris for X-ray and neutron diffraction.
O'Dell, W.B., Swartz, P.D., Weiss, K.L. and Meilleur. F
Acta Crystallographica Section F: Structural Biology Communications, 2017, 73(2), pp.70-78.

Analysis of Ribonucleotide 5′-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays
Lu G, Bluemling GR, Collop P, Hager M, Kuiper D, Gurale BP, Painter GR, De La Rosa A, Kolykhalov AA
Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e01967-16. doi:10.1128/AAC.01967-16. Print 2017 Mar.

2016

The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse
Gokhale A, Hartwig C, Freeman AH, Das R, Zlatic SA, Vistein R, Burch A, Carrot G, Lewis AF, Nelms S, Dickman DK, Puthenveedu MA, Cox DN, Faundez V
J Neurosci. 2016 Dec 7;36(49):12393-12411

Sortilin 1 modulates hepatic cholesterol lipotoxicity in mice via functional interaction with liver carboxylesterase 1
Li J, Wang Y, Matye D, Chavan H, Krishnamurthy P, Li F, Li T
J Biol Chem. 2016 Nov 23. pii: jbc.M116.762005. [Epub ahead of print]

Intrinsic Resistance of Burkholderia cepacia Complex to Benzalkonium Chloride
Ahn Y, Kim JM, Kweon O, Kim SJ, Jones RC, Woodling K, Gamboa da Costa G, LiPuma JJ, Hussong D, Marasa BS, Cerniglia CE
MBio. 2016 Nov 22;7(6). pii: e01716-16. doi: 10.1128/mBio.01716-16

Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres
Garcia-Exposito L, Bournique E, Bergoglio V, Bose A, Barroso-Gonzalez J, Zhang S, Roncaioli JL, Lee M, Wallace CT, Watkins SC, Opresko PL, Hoffmann JS, O'Sullivan RJ
Cell Rep. 2016 Nov 8;17(7):1858-1871. doi: 10.1016/j.celrep.2016.10.048

Siderophore vaccine conjugates protect against uropathogenic Escherichia coli urinary tract infection
Mike LA, Smith SN, Sumner CA, Eaton KA, Mobley HL
Proc Natl Acad Sci U S A. 2016 Nov 7. pii: 201606324. [Epub ahead of print]

Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration
Yao J, Jia L, Feathers K, Lin C, Khan NW, Klionsky DJ, Ferguson TA, Zacks DN
Autophagy. 2016 Oct 18:1-12. [Epub ahead of print]

Germinal-center kinase-like kinase co-crystal structure reveals a swapped activation loop and C-terminal extension
Marcotte D, Rushe M, M Arduini R, Lukacs C, Atkins K, Sun X, Little K, Cullivan M, Paramasivam M, Patterson TA, Hesson T, D McKee T, May-Dracka TL, Xin Z, Bertolotti-Ciarlet A, Bhisetti GR, Lyssikatos JP, Silvian LF
Protein Sci. 2016 Oct 11. doi: 10.1002/pro.3062. [Epub ahead of print]

Alterations in the human proteome following administration of valproic acid
Georgoff PE, Halaweish I, Nikolian VC, Higgins GA, Bonham T, Tafatia C, Remmer H, Menon R, Liu B, Li Y, Alam HB
J Trauma Acute Care Surg. 2016 Dec;81(6):1020-1027

Purification and identification of amylases released by the human pathogen Trichomonas vaginalis that are active towards glycogen
Smith RW, Brittingham A, Wilson WA
Mol Biochem Parasitol. 2016 Nov - Dec;210(1-2):22-31. doi: 10.1016/j.molbiopara.2016.08.002. Epub 2016 Aug 6

Functional characterization of apoptosis-associated speck-like protein (ASC) of the goldfish (Carassius auratus L.)
Xie J, Belosevic M
Dev Comp Immunol. 2016 Jul 19. pii: S0145-305X(16)30230-0. doi: 10.1016/j.dci.2016.07.013. [Epub ahead of print]

Detection of Pentosidine Cross-Links in Cell-Secreted Decellularized Matrices Using Time Resolved Fluorescence Spectroscopy
Debika Mitra, Hussain Fatakdawala, Michael Nguyen-Truong, Amy Creecy, Jeffry Nyman, Laura Marcu, and J. Kent Leach
ACS Biomater. Sci. Eng., Article ASAP DOI: 10.1021/acsbiomaterials.6b00029

APP may act as a substrate and a recognition unit for CRL4CRBN and Stub1 E3 ligases facilitating ubiquitination of proteins involved in presynaptic functions and neurodegeneration
Del Prete D, Rice RC, Rajadhyaksha AM, D'Adamio L
J Biol Chem. 2016 Jun 20. pii: jbc.M116.733626. [Epub ahead of print]

The methylcytosine dioxygenase Ten-Eleven Translocase-2 (tet2) enables elevated GnRH gene expression and maintenance of male reproductive function
Kurian JR, Louis S, Keen KL, Wolfe A, Terasawa E, Levine JE
Endocrinology. 2016 Jul 6:en20161087. [Epub ahead of print]

Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells
Cruz-Diaz N, Wilson BA, Pirro NT, Brosnihan KB, Marshall AC, Chappell MC
Peptides. 2016 Jun 15. pii: S0196781(16)30124-3. doi:10.1016/j.peptides.2016.06.005. [Epub ahead of print]

Inherent ER stress in pancreatic islet β cells causes self-recognition by autoreactive T cells in type 1 diabetes
Marré ML, Profozich JL, Coneybeer JT, Geng X, Bertera S, Ford MJ, Trucco M, Piganelli JD
J Autoimmun. 2016 May 9. pii: S0896-8411(16)30051-8. doi: 10.1016/j.jaut.2016.04.009. [Epub ahead of print]

Glutathione adducts induced by ischemia and deletion of glutaredoxin-1 stabilize HIF-1α and improve limb revascularization
Watanabe Y, Murdoch CE, Sano S, Ido Y, Bachschmid MM, Cohen RA, Matsui R
Proc Natl Acad Sci U S A. 2016 May 24;113(21):6011-6. doi: 10.1073/pnas.1524198113. Epub 2016 May 9

Lysine acetylation of the Mycobacterium tuberculosis HU protein modulates its DNA binding and genome organization
Ghosh S, Padmanabhan B, Anand C, Nagaraja V
Mol Microbiol. 2016 Jan 28. doi: 10.1111/mmi.13339. [Epub ahead of print]

SMG7 is a critical regulator of p53 stability and function in DNA damage stress response
Hongwei Luo, Lauren Cowen, Guowu Yu, Wenguo Jiang & Yi Tang
Cell Discovery 2, Article number: 15042 (2016)

Ingression Progression Complexes Control Extracellular Matrix Remodelling during Cytokinesis in Budding Yeast
Foltman M, Molist I, Arcones I, Sacristan C, Filali-Mouncef Y, Roncero C, Sanchez-Diaz A
PLoS Genet. 2016 Feb 18;12(2):e1005864. doi: 10.1371/journal.pgen.1005864.

Implications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing Domain
Rath P, Hilton JK, Sisco NJ, Van Horn WD
Biochemistry. 2016 Jan 12;55(1):114-24. doi: 10.1021/acs.biochem.5b00931. Epub

2015

Novel human-derived extracellular matrix induces in vitro and in vivo vascularization and inhibits fibrosis
Moore MC, Pandolfi V, McFetridge PS
Biomaterials. 2015 May;49:37-46. doi: 10.1016/j.biomaterials.2015.01.022.

Comparative genomics of Cluster O mycobacteriophages
Hatfull GF et al.
PLoS One. 2015 Mar 5;10(3):e0118725. doi: 10.1371/journal.pone.0118725

APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses
Fanutza T, Del Prete D, Ford MJ, Castillo PE, D'Adamio L
Elife. 2015 Nov 9;4. pii: e09743. doi: 10.7554/eLife.09743. [Epub ahead of print]

Towards aspirin-inspired self-immolating molecules which target the cyclooxygenases
Drake CR, Estévez-Salmerón L, Gascard P, Shen Y, Tlsty TD, Jones EF
Org Biomol Chem. 2015 Dec 7;13(45):11078-86. doi: 10.1039/c5ob01805f. Epub 2015

Quantitative Proteomic Analysis of Enriched Nuclear Fractions from BK Polyomavirus-Infected Primary Renal Proximal Tubule Epithelial Cells
Justice JL, Verhalen B, Kumar R, Lefkowitz EJ, Imperiale MJ, Jiang M
J Proteome Res. 2015 Oct 2;14(10):4413-24. doi: 10.1021/acs.jproteome.5b00737.

High-Throughput Screening Strategy Identifies Allosteric, Covalent Human D-Amino Acid Oxidase Inhibitor
Terry-Lorenzo RT, Masuda K, Sugao K, Fang QK, Orsini MA, Sacchi S, Pollegioni L
J Biomol Screen. 2015 Aug 21. pii: 1087057115600413. [Epub ahead of print]

Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma
Radon TP, Massat NJ, Jones R, Alrawashdeh W, Dumartin L, Ennis D, Duffy SW, Kocher HM, Pereira SP, Guarner Posthumous L, Murta-Nascimento C, Real FX, Malats N, Neoptolemos J, Costello E, Greenhalf W, Lemoine NR, Crnogorac-Jurcevic T
Clin Cancer Res. 2015 Aug 1;21(15):3512-21. doi: 10.1158/1078-0432.CCR-14-2467.

Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance
Swindell WR, Remmer HA, Sarkar MK, Xing X, Barnes DH, Wolterink L, Voorhees JJ, Nair RP, Johnston A, Elder JT, Gudjonsson JE
Genome Med. 2015 Aug 4;7(1):86. doi: 10.1186/s13073-015-0208-5. eCollection 2015

Mapping of post-translational modifications of spermatid-specific linker histone H1-like protein, HILS1
Laxmi MN, Gupta N, Satyanarayana RM
Proteomics. 2015 Aug 6. pii: S1874-3919(15)30092-0. doi:

A conserved Polϵ binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1
García-Rodríguez LJ, De Piccoli G, Marchesi V, Jones RC, Edmondson RD, Labib K
Nucleic Acids Res. 2015 Aug 6. pii: gkv799. [Epub ahead of print]

Dynamic arginine methylation of TNF receptor associated factor 6 regulates Toll-like receptor signaling
Tikhanovich I, Kuravi S, Artigues A, Villar MT, Dorko K, Nawabi A, Roberts B, Weinman SA
J Biol Chem. 2015 Jul 28. pii: jbc.M115.653543. [Epub ahead of print]

Selective recruitment of nuclear factors to productively replicating herpes simplex virus genomes
Dembowski JA, DeLuca NA
PLoS Pathog. 2015 May 27;11(5):e1004939. doi: 10.1371/journal.ppat.1004939.

Glucose-Regulated Phosphorylation of the PUF Protein Puf3 Regulates the Translational Fate of Its Bound mRNAs and Association with RNA Granules
Lee CD, Tu BP
Cell Rep. 2015 Jun 16;11(10):1638-50. doi: 10.1016/j.celrep.2015.05.014. Epub 2015 Jun 4

The N-ethylmaleimide-sensitive factor and dysbindin interact to modulate synaptic plasticity
Gokhale A, Mullin AP, Zlatic SA, Easley CA 4th, Merritt ME, Raj N, Larimore J, Gordon DE, Peden AA, Sanyal S, Faundez V
J Neurosci. 2015 May 13;35(19):7643-53. doi: 10.1523/JNEUROSCI.4724-14.2015

Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity
Carmi Y, Spitzer MH, Linde IL, Burt BM, Prestwood TR, Perlman N, Davidson MG, Kenkel JA, Segal E, Pusapati GV, Bhattacharya N, Engleman EG
Nature. 2015 May 7;521(7550):99-104. doi: 10.1038/nature14424. Epub 2015 Apr 29

Dynamic response of Mycobacterium vanbaalenii PYR-1 to BP Deepwater Horizon crude oil
Kim SJ, Kweon O, Sutherland JB, Kim HL, Jones RC, Burback BL, Graves SW, Psurny E, Cerniglia CE
Appl Environ Microbiol. 2015 Apr 17. pii: AEM.00730-15. [Epub ahead of print]

Mapping of Post-translational Modifications of Transition Proteins, TP1 and TP2 and Identification of Protein Arginine Methyltransferase 4 and Lysine Methyltransferase 7 as Methyltransferase for TP2
Nikhil G, Pradeepa MM, Anayat BU, Satyanarayana RM
J Biol Chem. 2015 Mar 28. pii: jbc.M114.620443. [Epub ahead of print]

Insulin resistance induces posttranslational hepatic Sortilin 1 degradation in mice
Li J, Matye DJ, Li T
J Biol Chem. 2015 Mar 23. pii: jbc.M115.641225. [Epub ahead of print]

Constitutive Phosphorylation of Cardiac Myosin Regulatory Light Chain in vivo
Audrey N. Chang, Pavan K. Battiprolu, Patrick M. Cowley, Guohua Chen, Robert D. Gerard, Jose R. Pinto, Joseph A. Hill, Anthony J. Baker, Kristine E. Kamm and James T. Stull
J Biol Chem. 2015 Mar 2. pii: jbc.M115.642165. [Epub ahead of print]

Examination of the skeletal proteome of the brittle star Ophiocoma wendtii reveals overall conservation of proteins but variation in spicule matrix proteins
Seaver RW, Livingston BT.
Proteome Science. 2015 Feb 7;13:7. doi: 10.1186/s12953-015-0064-7. eCollection 2015.

1,3-Dinitrobenzene Induces Age- and Region-Specific Oxidation to Mitochondria-Related Proteins in Brain.
Kubik LL, Landis RW, Remmer H, Bergin IL, Philbert MA.
Toxicological Sciences. 2015 Feb 24. pii: kfv015. [Epub ahead of print]

Annexin A2 promotes phagophore assembly by enhancing Atg16L(+) vesicle biogenesis and homotypic fusion.
Morozova K, Sidhar S, Zolla V, Clement CC, Scharf B, Verzani Z, Diaz A, Larocca JN, Hajjar KA, Cuervo AM, Santambrogio L.
Nature Communications. 2015 Jan 19;6:5856. doi: 10.1038/ncomms6856.

Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale
Cockburn DW, Orlovsky NI, Foley MH, Kwiatkowski KJ, Bahr CM, Maynard M, Demeler B, Koropatkin NM.
Molecular Biology. 2015 Jan;95(2):209-30. doi: 10.1111/mmi.12859. Epub 2014 Dec 19.

Gene Dosage in the Dysbindin Schizophrenia Susceptibility Network Differentially Affect Synaptic Function and Plasticity
Ariana P. Mullin, Madhumala K. Sadanandappa, Wenpei Ma, Dion K. Dickman, Krishnaswamy VijayRaghavan, Mani Ramasami, Subhabrata and Victor Faundez
The Journal of Neuroscience. 2015 Jan 7;35(1):325-38. doi: 10.1523/JNEUROSCI.3542-14.2015.

2014

Catalytically relevant electrostatic interactions of cytochrome P450c17 (CYP17A1) and cytochrome b5
Peng HM, Liu J, Forsberg SE, Tran HT, Anderson SM, Auchus RJ
J Biol Chem. 2014 Dec 5;289(49):33838-49. doi: 10.1074/jbc.M114.608919. Epub 2014

EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2complex to the base of primary cilia.
Pusapati GV, Hughes CE, Dorn KV, Zhang D, Sugianto P, Aravind L, Rohatgi R
Developmental Cell. 2014 Mar 10;28(5):483-96. doi: 10.1016/j.devcel.2014.01.021. Epub 2014 Feb 27.

Genomic variation. Impact of regulatory variation from RNA to protein
Battle A, Khan Z, Wang SH, Mitrano A, Ford MJ, Pritchard JK, Gilad Y.
Science. 2015 Feb 6;347(6222):664-7. doi: 10.1126/science.1260793. Epub 2014 Dec 18.

EMT-Associated Secretory Phenotype Predicts Survival in Lung Cancer Patients.
Ajaya Kumar Reka, Guoan Chen, Richard Jones, Ravi Amunugama, Sinae Kim, Alla Karnovasky Theodore J Standiford, David G. Beer, Gilbert S. Omenn, Venkateshwar G. Keshamouni
Journal of Carcinogenesis. 2014 Jun;35(6):1292-300. doi: 10.1093/carcin/bgu041. Epub 2014 Feb 7.

Phosphorylation of the Transcription Activator CLOCK Regulates Progression Through a ~24h Feedback Loop to Influence Circadian Period in Drosophila
Guruswamy Mahesh, EunHee Jeong, Fanny S. Ng, Yixiao Liu, Kushan Gunawardhana, Jerry H. Houl, Evrim Yildirim, Ravi Amunugama, Richard Jones, David L. Allen, Isaac Edery, Eun Young Kim, and Paul E. Hardin
Journal of Biological Chemistry. 2014 Jul 11;289(28):19681-93. doi: 10.1074/jbc.M114.568493. Epub 2014 May 28.

Discovering Protein Interactions and Characterizing Protein Function Using HaloTag Technology
Danette L. Daniels, Jacqui Mendez, Helene Benink, Andrew Niles, Nancy Murphy, Michael Ford, Richard Jones, Ravi Amunugama, David Allen, Marjeta Urh
Journal of Visualized Experiments. 2014 Jul 12;(89). doi: 10.3791/51553.

Sarcomere mutation-specific expression patterns in human hypertrophic cardiomyopathy
Helms AS, Davis FM, Coleman D, Bartolone SN, Glazier AA, Pagani F, Yob JM, Sadayappan S, Pedersen E, Lyons R, Westfall MV, Jones R, Russell MW, Day SM
Circulation: Cardiovascular Genetics. 2014 Aug;7(4):434-43. doi: 10.1161/CIRCGENETICS.113.000448. Epub 2014 Jul 16

Phosphorylation-regulated transitions in an oligomeric state control the activity of the sae2 DNA repair enzyme.
Fu Q, Chow J, Bernstein KA, Makharashvili N, Arora S, Lee CF, Person MD, Rothstein R, Paull TT
Molecular and Cellular Biology. 2014 Mar;34(5):778-93. doi: 10.1128/MCB.00963-13. Epub 2013 Dec 16. Erratum in: Mol Cell Biol. 2014 Nov 15;34(22):4213.

Localization and proteomic characterization of cholesterol-rich membrane microdomains in the inner ear
Paul V. Thomas, Andrew L. Cheng, Candice C. Colby, Liqian Liu, Chintan K. Patel, Lydia Josephs, R. Keith Duncan.
Journal of Proteomics. 2014 May 30;103:178-93. doi: 10.1016/j.jprot.2014.03.037. Epub 2014 Apr 5.

Bile Salts acts as effective protein-unfolding agents and instigators of disulfide stress in vivo
Cremers CM, Knoefler D, Vitvitsky V, Banerjee R, Jakob U
Proceeding of the National Academy of Sciences. 2014 Apr 22;111(16):E1610-9. doi: 10.1073/pnas.1401941111. Epub 2014 Apr 4.

Cell cycle-dependent chromatin shuttling of HBO1-JADE1 histone acetyl transferase (HAT) complex
Siriwardana NS, Meyer, Havasi A, Dominguez I, Panchenko MV
Cell Cycle. 2014;13(12):1885-901. doi: 10.4161/cc.28759. Epub 2014 Apr 16.

A New Paradigm for Enzymatic Control of α-Cleavage and β-Cleavage of the Prion Protein
Alex J. McDonald, Jessie P. Dibble, Eric G. B. Evans, Glenn L. Millhauser
Journal of Biological Chemistry. 2014 Jan 10;289(2):803-13. doi: 10.1074/jbc.M113.502351. Epub 2013 Nov 18.

Fish oil and fenofibrate prevented phosphorylation-dependent hepatic Sortilin 1 degradation in Western diet-fed mice
Jibiao Li, Lipeng Bi, Michelle Hulke and Tiangang Li
Journal of Biological Chemistry. 2014 Aug 8;289(32):22437-49. doi: 10.1074/jbc.M114.548933. Epub 2014 Jul 1.

Identification by GeLC-MS/MS of trypsin inhibitor in sarcoplasmic proteins of three tropical fish and characterization of their inhibitory properties
Siriphon Siriangkanakun, Eunice C.Y. Li-Chan and Jirawat Yongsawadigul
Journal of Food Science. 2014 Jul;79(7):C1305-14. doi: 10.1111/1750-3841.12521. Epub 2014 Jun 24.

Citrullination of ENA-78/CXCL5 results in conversion from a non-monocyte recruiting to a monocyte recruiting chemokine
Ken Yoshida, Olexandr Korchynskyi, Paul P. Tak, Takeo Isozaki, Jeffrey H. Ruth, Philip L. Campbell, Dominique L. Baeten, Danielle M. Gerlag, M. Asif Amin and Alisa E. Koch
Arthritis & Rheumatology. 2014 Oct;66(10):2716-27. doi: 10.1002/art.38750.

The ArgD N-terminal leader peptide of Staphylococcus aureus has cytolytic and amyloidogenic properties
Kelly Schwartz, Matthew D. Sekedat, Adnan K. Syeda, Brendan O’Hara, David E. Payne, Abigail Lamb and Blaise R. Boles
Infection and Immunity. 2014 Sep;82(9):3837-44. doi: 10.1128/IAI.02111-14. Epub 2014 Jun 30.

Hypomorphic PCNA mutation underlies a human DNA repair disorder
Emma L. Baple, Helen Chambers, Harold E. Cross, Heather Fawcett, Yuka Nakazawa, Barry A. Chioza, Gaurav V. Harlalka, Sahar Mansour, Ajith Sreekantan-Nair, Micahel A. Patton, Martina Muggenthaler, Philip Rich, Karin Wagner, Roselyn Coblentz, Constance K. Stein, James L. Last, A. Malcolm R. Taylor, Andrew P. Jackson, Tomoo Ogi, Alan R. Lehmann, Catherine M. Green and Andrew H. Cosby
The Journal of Clinical Investigation. 2014 Jul;124(7):3137-46. doi: 10.1172/JCI74593. Epub 2014 Jun 9.

An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration
Matthew L. Kutys & Kenneth M. Yamada
Nature Cell Biology. 2014 Sep;16(9):909-17. doi: 10.1038/ncb3026. Epub 2014 Aug 24.

Human secreted tau increases amyloid-beta production
Jessica Bright, Sami Hussain, Vu Dang, Sarah Wright, Bonnie Cooper, Tony Byun, Carla Ramos, Andrew Singh, Graham Parry, Nancy Stagliano, Irene Griswold-Prenner
Neurobiology of Aging. 2015 Feb;36(2):693-709. doi: 10.1016/j.neurobiolaging.2014.09.007. Epub 2014 Sep 16.

Mapping Post-translational Modifications of Mammalian Testicular specific Histone Variant TH2B in Tetraploid and Haploid Germ cells and their implications on the Dynamics of Nucleosome structure
Satya Krishna Pentakota, Sankaran Sandhya, Arun P Sikarwar, Nagasuma Chandra, and Manchanahalli R Satyanarayana Rao
Journal of Proteome Research. 2014 Dec 5;13(12):5603-17. doi: 10.1021/pr500597a. Epub 2014 Oct 6.

Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection
Makharashvili N, Tubbs AT, Yang SH, Wang H, Barton O, Zhou Y, Deshpande RA, Lee JH, Lobrich M, Sleckman BP, Wu X, Paull TT.
Molecular Cell. 2014 Jun 19; 54(6):1022-33. doi: 10.1016/j.molcel.2014.04.011. Epub 2014 May 15

2013

Flagellum density regulates Proteus mirabilis swarmer cell motility in viscous environments
Tuson HH, Copeland MF, Carey S, Sacotte R, Weibel DB
J Bacteriol. 2013 Jan;195(2):368-77. doi: 10.1128/JB.01537-12.

Age-related carbonylation of fibrocartilage structural proteins drives tissuedegenerative modification.
Scharf B, Clement CC, Yodmuang S, Urbanska AM, Suadicani SO, Aphkhazava D, Thi MM, Perino G, Hardin JA, Cobelli N, Vunjak-Novakovic G, Santambrogio L
Chemistry & Biology. 2013 Jul 25;20(7):922-34. doi: 10.1016/j.chembiol.2013.06.006.

Eukaryotic Replisome components cooperate to process histones during chromosome replication
Magdalena Foltman, Cecile Evrin, Giacomo De Piccoli, Richard C. Jones, Rick D. Edmondson, Yuki Katou, Ryuichiro Nakato, Katsuhiko Shirahige and Karim Labib
Cell Reports. 2013 Mar 28;3(3):892-904. doi: 10.1016/j.celrep.2013.02.028. Epub 2013 Mar 14.

Impaired assembly and post-translational regulation of 26S Proteasome in human end stage heart failure
Sharlene Day, Andras Divald, Ping Wang, Frank Davis, Sarah Bartolone, Richard Jones and Saul Powell
Circulation: Heart Failure. 2013 May;6(3):544-9. doi: 10.1161/CIRCHEARTFAILURE.112.000119. Epub 2013 Mar 20

Mutual Exclusivity of MED12/MED12L, MED13/13L, and CDK8/19 Paralogs Revealed within the CDK-Mediator Kinase Module
Danette L. Daniels, Michael Ford, Marie K. Schwinn, Hélène Benink, Matthew D. Galbraith, Ravi Amunugama, Richard Jones, David Allen, Noriko Okazaki, Hisashi Yamakawa, Futaba Miki, Takahiro Nagase, Joaquín M. Espinosa, and Marjeta Urh
Journal of Proteomics & Bioinformatics. S2:004 (2013)

Primate transcript and protein expression levels evolve under compensatory selection pressures
Khan Z, Ford MJ, Cusanovich DA, Mitrano A, Pritchard JK, Gilad Y
Science. 2013 Nov 29;342(6162):1100-4. doi: 10.1126/science.1242379. Epub 2013 Oct 17.

Protein expression profiles of human lymph and plasma mapped by 2D-DIGE and 1D SDS-PAGE coupled with nanoLC-ESI-MS/MS bottom-up proteomics
Cristina C. Clement, David Aphkhazava, Edward Nieves, Myrasol Callaway, Waldemar Olszewski, Olaf Rotzschke, Laura Santambrogio
Journal of Proteomics. 2013 Jan 14;78:172-87. doi: 10.1016/j.jprot.2012.11.013. Epub 2012 Nov 30.

Mcm8 and Mcm9 form a complex that functions in homologous recombination repair induced by DNA interstrand crosslinks
Nishimura K, Ishiai M, Horikawa K, Fukagawa T, Takata M, Takisawa H, Kanemaki MT
Molecular Cell. 2012 Aug 24;47(4):511-22. doi: 10.1016/j.molcel.2012.05.047. Epub 2012 Jul 5.

Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation
Natasha T. Snider, Jessica M. Leonard, Raymond Kwan, Nicholas W. Griggs, Liangyou Rui and M. Bishr Omary
The Journal of Cell Biology. 2013 Feb 4;200(3):241-7. doi: 10.1083/jcb.201209028. Epub 2013 Jan 28.

Alix serves as an adaptor that allows human parainfluenza virus type 1 to interact with the host cell ESCRT system
Boonyaratanakornkit J, Schomacker H, Collins P, Schmidt A
PLoS One. 2013;8(3):e59462. doi: 10.1371/journal.pone.0059462. Epub 2013 Mar 19.

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
Rachel Deplus, Benjamin Delatte, Marie K Schwinn, Matthieu Defrance, Jacqui Mendez, Nancy Murphy, Mark A. Dawson, Michael Volkmar, Pascale Putmans, Emile Calonne, Alan H Shih, Ross L Levine, Olivier Bernard, Thomas Mercher, Eric Solary, Marjeta Urh, Danette L Daniels and Francois Fuks.
The EMBO Journal. 2013 Mar 6;32(5):645-55. doi: 10.1038/emboj.2012.357. Epub 2013 Jan 25.

A plant-produced protective antigen vaccine confers protection in rabbits against a lethal aerosolized challenge with Bacillus anthracis Ames spores
Chichester JA, Manceva SD, Rhee A, Coffin MW, Musiychuk K, Mett V, Shamloul, Norikane J, Streatfield SJ, Yusibov V.
Human Vaccines and Immunotherapeutics. 2013 Mar;9(3):544-52. Epub 2013 Jan 16.

Lamin aggregation is an early sensor of porphyria-induced liver injury
Singla A, Griggs NW, Kwan R, Snider NT, Maitra D, Ernst SA, Herrmann H, Omary MB
Journal of Cell Science. 2013 Jul 15;126(Pt 14):3105-12. doi: 10.1242/jcs.123026. Epub 2013 May 2.

The WASH Complex, an Endosomal Arp2/3 Activator, Interacts with the Hermansky-Pudlak Syndrome Complex BLOC-1 and its Cargo Phosphatidylinositol-4-kinase Type II Alpha
Ryder PV, Vistein R, Gokhale A, Seaman MN, Puthenveedu M, Faundez V
Molecular and Cellular Biology. 2013 Jul;24(14):2269-84. doi: 10.1091/mbc.E13-02-0088. Epub 2013 May 15.

Tissue specificity of decellularized rhesus monkey kidney and lung scaffolds
Nakayama KH, Lee CC, Batchelder CA, Tarantal AF.
PLoS One. 2013 May 22;8(5):e64134. doi: 10.1371/journal.pone.0064134. Print 2013.

Proteomic analysis of Chlorella vulgaris: Potential targets for enhanced lipid accumulation
Guarnieri MT, Nag A, Yang S, Pienko PT
Journal of Proteomics. 2013 Nov 20;93:245-53. doi: 10.1016/j.jprot.2013.05.025. Epub 2013 Jun 5.

Rab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid droplets
Salloum S, Wang H, Ferguson C, Parton RG, Tai AW
PLoS Pathogens. 2013;9(8):e1003513. doi: 10.1371/journal.ppat.1003513. Epub 2013 Aug 1.

KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors
Black JC, Manning AL, Van Rechem C, Kim J, Ladd B, Cho J, Pineda CM, Murphy N, Daniels DL, Montagna C, Lewis PW, Glass K, Allis CD, Dyson NJ, Getz G, Whetstine JR
Cell. 2013 Aug 1;154(3):541-55. doi: 10.1016/j.cell.2013.06.051. Epub 2013 Jul 18.

The TREX1 C-terminal region controls cellular localization through ubiquitination
Orebaugh CD, Fye JM, Harvey S, Hollis T, Wilkinson JC, Perrino FW
Journal of Biological Chemistry. 2013 Oct 4;288(40):28881-92. doi: 10.1074/jbc.M113.503391. Epub 2013 Aug 26

Temporal Association of Herpes Simplex Virus ICP4 with Cellular Complexes Functioning at Multiple Steps in PolII Transcription
Wagner LM, Deluca NA
PLoS One. 2013 Oct 11;8(10):e78242. doi: 10.1371/journal.pone.0078242. eCollection 2013.

Methylation of structural components of the axoneme occurs during flagellar disassembly
Werner-Peterson R, Sloboda RD
Biochemistry. 2013 Nov 26;52(47):8501-9. doi: 10.1021/bi4011623. Epub 2013 Nov 12.

2012

Ubiquitination of neuronal nitric-oxide synthase in the calmodulin-binding site triggers proteasomal degradation of the protein
Clapp KM, Peng HM, Jenkins GJ, Ford MJ, Morishima Y, Lau M, Osawa Y
J Biol Chem. 2012 Dec 14;287(51):42601-10. doi: 10.1074/jbc.M112.412494.

Proteome of formalin-fixed paraffin-embedded pancreatic ductal adenocarcinomaand lymph node metastases.
Naidoo K, Jones R, Dmitrovic B, Wijesuriya N, Kocher H, Hart IR, Crnogorac-Jurcevic T
The Journal of Pathology. 2012 Apr;226(5):756-63. doi: 10.1002/path.3959. Epub 2012 Jan 17. Erratum in: J Pathol. 2012 Aug;227(4):e8.

Characterization of differential protein tethering at the plasma membrane in response to Epidermal Growth Factor signaling
B.D. Looyenga and J.P. Mackeigan
Journal of Proteome Research. 2012 Jun 1;11(6):3101-11. doi: 10.1021/pr201077d. Epub 2012 May 15.

Preimplantation Factor (PIF*) reverses neuroinflammation while promoting neural repair in EAE model
L. Weiss, R. Or, R.C. Jones, R. Amunugama, L. JeBailey, S. Ramu, S.A. Bernstein, Z. Yekhtin, O. Almogi-Hazan, R. Shainer, I. Reibstein, A.O. Vortmeyer, M.J. Paidas, M. Zeira, S. Slavin, E.R. Barnea
Journal of the Neurological Sciences. 2012 Jan 15;312(1-2):146-57. doi: 10.1016/j.jns.2011.07.050. Epub 2011 Oct 13.

Canonical Wnt signaling regulates Slug activity and links epithelial–mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression
Zhao-Qiu Wu, Xiao-Yan Li, Casey Yuexian Hu, Michael Ford, Celina G. Kleer, Stephen J. Weiss.
Proceedings of the National Academy of Sciences. 2012 Oct 9;109(41):16654-9. doi: 10.1073/pnas.1205822109. Epub 2012 Sep 24.

β2-Syntrop[hin and PAr-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity
Natalie Mack, Andrew Porter, Helen Porter, Helen Whalley, Juliane Schwarz, Richard Jones, Azharuddin Sajid Syed Khaja, Anders Bjartell, Kurt Anderson and Angeliki Malliri
Nature Cell Biology. 2012 Nov;14(11):1169-80. doi: 10.1038/ncb2608. Epub 2012 Oct 28.

Cycling of Etk and Etp phosphporylation states is involved in formation of group 4 capsule by Escherichia coli
C. Nadler, S. Koby, A.C. Johnson, K.C. Suddala, K. Sathiyamoorthy, B.E. Smith, M.A. Saper & I. Rosenshine
PLoS One. 2012;7(6):e37984. doi: 10.1371/journal.pone.0037984. Epub 2012 Jun 4.

G-protein signaling modulator-3 regulates heterotrimeric G-protein dynamics through dual association with Gß and Gαi protein subunits
Giguere PM, Laroche G, Oestreich EA, Siderovski DP
Journal of Biological Chemistry. 2012 Feb 10;287(7):4863-74. doi: 10.1074/jbc.M111.311712. Epub 2011 Dec 13.

A Conserved motif in the C-terminal of DNA polymerase α tether primase to the eukaryotic replisome
M.L. Kilkenny, G. De Piccoli, R.L. Perera, L. Pellegrini
Journal of Biological Chemistry. 2011 Dec 2;286(48):41826-37. doi: 10.1074/jbc.M111.305888. Epub 2011 Oct 10.

Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network
P. Perez-Cornejo, A. Gokhale, C. Duran, Y. Cui, Q. Xiao, H. Criss Hartzell and V. Faundez
Proceedings of the National Academy of Sciences. 2012 Jun 26;109(26):10376-81. doi: 10.1073/pnas.1200174109. Epub 2012 Jun 8.

Functional Amyloids Composed of Phenol Soluble Modulins Stabilize Staphylococcus aureus Biofilms
K. Schwartz, A.K. Syed, R.E. Stephenson, A.H. Rickard, B.R. Boles
PLoS Pathogens. 2012;8(6):e1002744. doi: 10.1371/journal.ppat.1002744. Epub 2012 Jun 7.

Quantitative Proteomic and Genetic Analyses of the Schizophrenia Susceptibility Factor Dysbindin Identify Novel Roles of the Biogenesis of Lysosome-Related Organelles Complex 1
Gokhale A, Larimore J, Werner E, So L, Moreno-De-Luca A, Lese-Martin C, Lupashin VV, Smith Y, Faundez V
The Journal of Neuroscience. 2012 Mar 14;32(11):3697-711. doi: 10.1523/JNEUROSCI.5640-11.2012.

Alcohol-induced alterations in maternal uterine endothelial proteome: A quantitative iTRAQ mass spectrometric approach
Ramadoss J, Magness RR
Reproductive Toxicology. 2012 Dec;34(4):538-44. doi: 10.1016/j.reprotox.2012.08.008. Epub 2012 Sep 5.

Differential proteomics identifies pdia3 as a novel chemoprevention target in human colon cancer
Menoret A, Drew DA, Miyamoto S, Nakanishi M, Vella AT, Rosenberg DW
Molecular Carcinogenesis. 2014 Feb;53 Suppl 1:E11-22. doi: 10.1002/mc.21986. Epub 2012 Dec 19.

Production of non-glycosylated recombinant proteins in Nicotiana benthamiana plants by co-expressing bacterial PNGase F
Mamedov T, Ghosh A, Jones RM, Mett V, Farrance CE, Musiychuk K, Horsey A, Yusibov V
Plant Biotechnology Journal. 2012 Sep;10(7):773-82. doi: 10.1111/j.1467-7652.2012.00694.x. Epub 2012 Apr 23

Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for In Vitro Investigation
Adam J. Booth, Ryan Hadley, Ashely M. Cornett, Alyssa A. Dreffs, Stephanie A. Matthes, Jessica L. Tsui, Kevin Weiss, Jeffrey C. Horowitz, Vincent F. Fiore, Thomas H. Barker, Bethany B. Moore, Fernando J. Martinez, Laura E. Niklason and Eric S. White
American Journal of Repiratory and Critical Care Medicine. 2012 Nov 1;186(9):866-76. doi: 10.1164/rccm.201204-0754OC. Epub 2012 Aug 30.

2011

Structural analysis of human and macaque mAbs 2909 and 2.5B: implications for the configuration of the quaternary neutralizing epitope of HIV-1 gp120.
Spurrier B, Sampson JM, Totrov M, Li H, O'Neal T, Williams C, Robinson J, Gorny MK, Zolla-Pazner S, Kong XP
Structure. 2011 May 11;19(5):691-9. doi: 10.1016/j.str.2011.02.012.

Preimplantation Factor (PIF) analog prevents Diabetes onset (adoptive transfer and spontaneous) by preserving pancreatic function in NOD mice
L. Weiss, S. Bernstein, R. Jones, R. Amunugama, D. Krizman, L. JeBailey, S. Slavin, and E.R. Barnea,
Journal of the Neurological Sciences. 2012 Jan 15;312(1-2):146-57. doi: 10.1016/j.jns.2011.07.050. Epub 2011 Oct 13.

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells
Neganova, F. Vilella, S.P. Atkinson, M. Lloret, J. Passos, T. von Zglinicki, J-E O’Connor, D. Burks, R. Jones, L. Armstrong and M. Lako,
Stem Cells. 2011 Apr;29(4):651-9. doi: 10.1002/stem.620.

Mcm2-7 form double hexamers at licensed origins in xenopus egg extract
Gambus, G.Khoudoli, R. Jones and J. Blow.
The Journal of Biological Chemistry. 2011 Apr 1;286(13):11855-64. doi: 10.1074/jbc.M110.199521. Epub 2011 Jan 31.

Inhibition of Staphylococcus aureus MN8 by Lysostaphin-Expressing Lactobacillus plantarum WCFS1 in a Modified Genital Tract Secretion Medium
H. Liu, Y. Gao, L. Yu, R.C. Jones, C.A. Elkins, and M.E. Hart,
Applied and Environmental Microbiology. 2011 Dec;77(24):8500-8. doi: 10.1128/AEM.06755-11. Epub 2011 Oct 7.

Examination of Triacylglycerol Biosynthetic Pathways via De Novo Transcriptomic and Proteomic Analyses in an Unsequenced Microalga
M.T. Guarnieri, A. Nag, S.L. Smolinski, A. Darzins, M. Seibert
PLoS One. 2011;6(10):e25851. doi: 10.1371/journal.pone.0025851. Epub 2011 Oct 17.

Hemoglobin promotes Staphylococcus aureus nasal colonization
M. Pynnonen , R.E. Stephenson, K. Schwartz , M. Hernandez, B.R. Boles
PLoS Pathogens. 2011 Jul;7(7):e1002104. doi: 10.1371/journal.ppat.1002104. Epub 2011 Jul 7.

Interaction of sororin protein with polo-like kinase 1 mediates resolution of chromosomal arm cohesion
Nenggang Zhang, Anil K. Panigrahi, Qilong Mao and Debananda Pati
Journal of Biological Chemistry. 2011 Dec 2;286(48):41826-37. doi: 10.1074/jbc.M111.305888. Epub 2011 Oct 10.

2010

Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubuleintegrity.
Tian G, Thomas S, Cowan NJ.
Cytoskeleton (Hoboken). 2010 Nov;67(11):706-14. doi: 10.1002/cm.20480.

SUMOylation of the GTPase Rac1 regulates its activity and is required for optimal cell migration
S. Castillo-Lluva, M.H. Tatham, R. C. Jones, R.D. Edmondson, R.T. Hay and A. Malliri
Nature Cell Biology. 2010 Nov;12(11):1078-85. doi: 10.1038/ncb2112. Epub 2010 Oct 10.

A genomic and proteomic investigation of the impact of preimplantation factor on human decidual cells
M.J. Paidas, G Krikun, S.J. Huang, R. Jones, M. Romano; J. Annunziato, E.R. Barnea
American Journal of Obstetrics and Gynecology. 2010 May;202(5):459.e1-8. doi: 10.1016/j.ajog.2010.03.024.