Latest News

New Promega/MS Bioworks Pubhub article

Two alternative proteinases, Asp-N Sequencing Grade and Glu-C Sequencing Grade are available from Promega to expand options for protein digestion.  Asp-N, Sequencing Grade, is a metallo proteinases that preferentially cleaves at the N-terminus of aspartic and cysteic acid residues. Glu-C is a serine proteinases that cleaves with high specificity at the C-terminus of glutamic and […]

New Promega/MS Bioworks Pubhub article

Alternative proteases can improve mass spectrometry protein analysis by using unique digestion conditions or complimentary cleavage specificity. In this article, we use four alternative proteases: Arg-C, elastase, thermolysin and pepsin, and show typical applications for these proteases and how their use can improve mass spectrometry analysis. We demonstrate the advantages of these proteases using various […]

QMUL and MS Bioworks identify proteins that can differentiate PDAC and LN formalin-fixed paraffin-embedded (FFPE) tissues

Tatjana Crnogorac-Jurcevic and her colleagues from Barts Cancer Institute, Queen Mary University of London (QMUL) and MS Bioworks report on progress in understanding pancreatic ductal adenocarcinoma (PDAC), a major cause of cancer-related death.  Dr. Crnogorac-Jurcevic from the Molecular Oncology center at Barts used proteomics to study primary tumors and matched lymph node (LN) metastases.  The […]

Emory Scientists use SILAC data to study schizophrenia susceptibility factor dysbindin

A study lead by Victor Faundez, Associate Professor of Cell Biology at Emory University reports the “Quantitative Proteomic and Genetic Analyses of the Schizophrenia Susceptibility Factor Dysbindin Identify Novel Roles of the Biogenesis of Lysosome-Related Organelles Complex 1” in The Journal of Neuroscience (14 March 2012, 32, 3637-3651).  The Biogenesis of Lysosome-related Organelles Complex 1 […]

Natasha Snider wins APS Award

Congratulations to Dr. Natasha Snider (Department of Molecular and Integrative Physiology, University of Michigan) winner of the American Physiological Society Research Recognition Award of the Gastrointestinal and Liver Physiology Section.  Natasha will be presenting her work on the regulation of keratin intermediate filaments by lysine acetylation at the upcoming Experimental Biology meeting in San Diego […]

Recent Successes from MS Bioworks Clients and Collaborators

Kathleen Stringer, Pharm.D., Associate Professor of Clinical Pharmacy at the University of Michigan has been invited to present data in the Rare Pediatric Lung Disease: Expanding our Understanding Mini-Symposium at the upcoming American Thoracic Society in San Francisco, CA.  Dr. Stringer will be presenting her work on the complementary approaches of proteomics and immunophenotyping and […]

New Promega/MS Bioworks Pubhub article

Identifying protein subunits is a routine application of mass spectrometry. With advances in this technology, characterization of complexes has become accessible to more researchers. Using the human proteasome as our model complex, we demonstrate how new commercial technologies and services allow researchers to quickly characterize a complex with little upfront effort. We combined HaloTag® technology […]