OLink® Reveal Plasma Proteomics
NGS-Based Proteomics
High-throughput protein quantification using Next-Generation Sequencing
Quantify ~1,100 biologically relevant proteins from just 4?µL of plasma, serum, or other matrices, with high sensitivity, excellent reproducibility, and minimal hands-on time.
Ideal for researchers looking to add robust proteomic data to genomics, biomarker, or translational studies.
>1,000
Proteins covering the proteome
4µL
Plasma, serum and more
2 weeks
86 to 344 samples
The University of Michigan BRCF Advanced Genomics Core is the sequencing service partner for Olink’s Reveal Assay offered through MS Bioworks.
Ideal uses for NGS-Proteomics
NGS plasma proteomics solutions offer a an alternative to mass spectrometry based assays. The Reveal panel is defined ahead of time and the workflow can be readily ported to many labs with the ability to plug into existing sequencing pipelines.
The reveal panel can be useful for many applications including:
- Broad biomarker discovery in inflammation, immune response, oncology, metabolic and population?scale studies
- Proteogenomics and pQTL research—helps link protein variation to genetics
- Adding proteomics data to existing genomics/transcriptomics studies without needing expert proteomics workflows
Olink® Reveal Documentation
Identification of potential biomarkers of prediabetes and diabetes using Olink Reveal
Olink® Reveal Chronic Lymphocytic Leukemia Case Study
Why scientists are choosing Olink Reveal
It’s fast, scalable, and easy to run without sacrificing data quality. Here are six reasons it’s becoming a go-to for proteomics and plasma discovery.
Broad yet focused coverage
You get data on ~1,000 proteins—particularly ones tied to immune pathways, inflammation, disease biology, and genetics (cis?pQTLs)
Minimal sample & hands?on effort
Requires only ~4?µL of sample; prep time is ~1.5?days with under ~2.5?hours of hands?on work
NGS?based readout
Uses your existing sequencer — no need for proteomics instrumentation.
Compatible with NovaSeq™, NextSeq™, and other common platforms.
High sensitivity and reproducibility
Detects low-abundance proteins with femtogram/mL sensitivity.
Intra- and inter-assay CVs average under 10%, ensuring consistent results.
Cost?effective and streamlined
Run up to 86 samples per plate.
Perfect for high-throughput studies without breaking your budget.
Fast, integrated turnaround
From sample to data in under a week with streamlined prep and analysis.? Accelerates timelines for discovery, validation, and translational research.
Welcome to the New Era of Proteomics
Mass spectrometry-based proteomics has changed dramatically in recent years. Let’s talk about how deep, unbiased proteome screening can accelerate your drug discovery. Please reach out to info@msbioworks.com or call 1-888-960-0650
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